prothrombin time


prothrombin time
= PT
the time taken for blood clotting to occur in a sample of blood to which calcium and thromboplastin have been added. A prolonged PT (compared with a control sample) indicates a deficiency of coagulation factors, which – with calcium and thromboplastin – are required for the conversion of prothrombin to thrombin to occur in the final stages of blood coagulation. Measurement of PT is used to control anticoagulant therapy (e.g. with warfarin).
See: INR

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  • prothrombin time — noun : the time required for a particular specimen of prothrombin to induce blood plasma clotting under standardized conditions in comparison with a time of between 11.5 and 12 seconds for normal human blood …   Useful english dictionary

  • one-stage prothrombin time — prothrombin t …   Medical dictionary

  • Время Протромбиновое (Prothrombin Time (Pt)) — время, необходимое для свертывания крови после добавления к исследуемому образцу крови кальция и тромбопластина. Большое протромбиновое время (по сравнению с контрольным образцом) свидетельствует о наличии в организме дефицита коагулирующих… …   Медицинские термины

  • Prothrombin — is a coagulation (clotting) factor. It is needed for the normal clotting of blood. There is a cascade of biochemical events that leads to the formation of the final clot. In this cascade, prothrombin is a precursor to thrombin. Because… …   Medical dictionary

  • prothrombin test — prothrombin time. 2. two stage prothrombin time t …   Medical dictionary

  • Prothrombin complex concentrate — (PCC) (trade name Beriplex or Octaplex[1]) is a combination of blood clotting factors II, VII, IX and X, as well as protein C and S.[1] It reverses the effect of warfarin (a coumarin anti coagulant) and is used in cases of significant bleeding in …   Wikipedia

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  • time — 1. That relation of events which is expressed by the terms past, present, and future, and measured by units such as minutes, hours, days, months, or years. 2. A certain period during which something definite or determined is done. SYN: tempus (2) …   Medical dictionary